What Is Leaky Gut Syndrome? 4 Things To Know About Intestinal Permeability

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Over 2,000 years ago, Hippocrates famously stated that "all disease begins in the gut." Modern medicine is only beginning to catch up with this early prediction. One of the most significant medical discoveries as of late is of the huge role the gut plays in the rest of our health. Because of this, many ailments can be traced back to leaky gut syndrome, also known as intestinal permeability.

Our intestines are lined with cells called tight-junction proteins (TJ proteins), Josh Axe, DNM, CNS, DC, founder of Ancient Nutrition and DrAxe.com and author of the upcoming KETO DIET, tells Bustle. For someone with a healthy gut, these cells let nutrients enter the bloodstream and keep waste products called xenobiotics out. But when your gut is leaky, it can't do that.

"Leaky Gut occurs when the lining of the gut is porous and allows food particles, bacteria, toxins, and environmental pathogens through the lining of the gut into the bloodstream," functional medicine doctor Wendie Trubow, MD tells Bustle. "When that occurs, the immune system recognizes all these foreign items and begins to mount an immune response, and can cause the system to be on high alert." A doctor might diagnose Leaky Gut based on a number of tests that measure your levels of the protein zonulin, which lets food particles pass through the intestinal wall, among other things.

Here are some facts to know about Leaky Gut Syndrome, according to experts.